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INTRODUCTION: The purpose of this study was to evaluate the biocompatibility of calcium aluminate cement (EndoBinder) in subcutaneous tissue of rats. METHODS: Fifteen rats, weighing 300 g, were separated into 3 groups (n = 5) in accordance with the time of death (7, 21, 42 days). Two incisions were made in the dorsal subcutaneous tissue of each rat in which were implanted 2 polyethylene tubes filled with the test materials, EndoBinder (EB) and Grey MTA (GMTA). The external tube walls were considered the negative control group (CG). After 7, 21, and 42 days, animals were killed, obtaining 5 samples per group, at each time interval of analysis. RESULTS: From the morphologic and morphometric analyses by using a score of (0-3) (50, 100, and 400×), results showed absence of inflammatory reaction (0) for EB after 42 days. However, for GMTA, a slight inflammatory reaction (1) was observed after 42 days, which means the persistence of a chronic inflammatory process. When compared w

Capasio is being developed as a new generation of endodontic material with potential use as a root-end filling material. The aim of this study was to compare the ability of Capasio and mineral trioxide aggregate (MTA) to penetrate human dentinal tubules and examine the interaction of Capasio and MTA with a synthetic tissue fluid (STF) and root canal walls in extracted human teeth. Results Penetration of Capasio into dentinal tubules was observed at all levels. No penetration of MTA into dentinal tubules was observed at any level. Both Capasio and MTA formed apatite crystals in the supernatant, on their exposed surfaces, and in the interfacial layers that were similar in structure and elemental composition when evaluated by using SEM and EDXA. XRD analysis of these crystals corresponds with those reported for hydroxyapatite. Conclusions When used as a root-end filling material, Capasio is more likely to penetrate dentinal tubules. Both Capasio and MTA promote apatite

iRoot BioAggregate - Root Canal Repair Material - BioAggregate Root Canal Repair Material is a biocompatible pure white powder composed of ceramic nano-particles. Upon mixing BioAggregate with BioA Liquid, the hydrophilic BioAggregate Powder promotes cementogenesis and forms a hermetic seal inside the root canal. Its effectiveness to clinically block off bacterial infections. Ease of material manipulation and superior quality make BioAggregate the most innovative and unique root canal repair material on the market. - Applications: 1. Repair of Root Perforation 2. Repair of Root Resorption 3. Root End Filling 4. Apexification 5. Pulp Capping - Features & Benefits: 1. Aluminum-Free Composition The effects of aluminum poisoning can range from subtle symptoms to serious diseases. BioAggregate is completely aluminum free and will not pose any toxic threat to the human body. 2. Biocompatibility BioAggregate is more biocompatible than any other root end filling and repair materials.

EndoSequence BC RRM EndoSequence® BC RRM™ (Root Repair Material) is available in two specifically formulated consistencies (syringable paste or condensable putty) and contains many of the same characteristics as BC Sealer™. The favorable handling properties, increased strength and shortened set time make BC RRM highly resistant to washout and ideal for all root repair and pulp capping procedures. Research and countless cases confirm that BC RRM is highly biocompatible and osteogenic. Join thousands of others that have set aside their spatulas and joined the BC RRM revolution! SUPERIOR HANDLING EXCELLENT HEALING Premixed-syringable paste or putty consistency Shortened Set Time – 2 hours vs. 4+ hours with others Highly Resistant to Washout EXCELLENT HEALING Highly Biocompatible Osteogenic Anti-bacterial (+12 pH) Applications: Root Endo Filling (Retrograde fills), Repair of Root Perforation, Repair of Root Resorption, Apexification, Pulp Capping Composition, Ca